Tesar Laboratory

The Tesar Laboratory sits at the interface between stem cell biology and developmental neuroscience. They use pluripotent stem cells to model neurological development and disease with a specific focus on glial cells in the central nervous system – oligodendrocytes and astrocytes. The Tesar Lab is interested in the molecular mechanisms by which cells acquire glial fate and function during development and maintain their functionality throughout life. They leverage this knowledge to define the cellular and molecular dysfunction that underlies certain neurological diseases and strive to develop meaningful therapeutic interventions using high throughput chemical screening and other approaches.